The different types of pyrimidine dimers each have distinct structures and implications for DNA integrity. A cyclobutane dimer (CPD) features a four-membered ring formed by the fusion of …

A pyrimidine dimer is an intrastrand DNA cross-link caused by exposure to ultraviolet light, which can block DNA replication and transcription. Various DNA repair mechanisms exist to remove …

2025年7月28日 · Pyrimidine dimers are a form of DNA damage where two adjacent pyrimidine bases on the same DNA strand become linked. These bases, usually cytosine or thymine, …

The major type of damage induced by UV light is the formation of pyrimidine dimers, in which adjacent pyrimidines on the same strand of DNA are joined by the formation of a cyclobutane …

Pyrimidine dimer refers to a type of DNA damage that occurs when two adjacent pyrimidine bases (usually thymine or cytosine) become covalently linked due to absorption of short-wavelength …

Pyrimidine dimers are a type of DNA damage that occurs when two adjacent pyrimidine bases, usually thymine, bond together due to ultraviolet (UV) radiation.

Notably, pyrimidine dimers contribute to sunburn and melanin production, and are a primary factor in melanoma development in humans. Pyrimidine dimers encompass several types, each with …

The different types of pyrimidine dimers each have distinct structures and implications for DNA integrity. A cyclobutane dimer (CPD) features a four-membered ring formed by the fusion of …

2025年4月29日 · Learn how pyrimidine dimers disrupt DNA function, affect repair mechanisms, and contribute to mutations that may lead to cancer development.

Pyrimidine dimers are molecular lesions formed from thymine or cytosine bases in DNA via photochemical reactions,[1][2] commonly associated with direct DNA damage.[3]